Working Group 4
WG4. Mathematical & Computational Modelling
Integrating multi-omics and radiomics data with AI/ML and mathematical modelling to advance precision medicine and AI-guided practice.
WG4
Objectives
Mathematical & Computational Modelling (Theme 4) integrates genotypic, multi-omics, radiomics and real-world data into AI/ML frameworks for precision medicine — building omics- and radiomics-specific models and fusing them with a variable-decision neural network approach.
- Objectives. To discover liquid-biopsy biomarkers and neuro-imaging markers for diagnosis and prognosis of brain cancers. Relevant to RCO1, RCO4 and RCO5.
- Tasks. T4.1 Data resource collection and integration strategies; T4.2 Create a pan-European brain cancer FAIR-aware database and biobank; T4.3 WG4 meetings.
- Activities. Involved in all MC and WG4 meetings, organisation of a WG4/WG5-focused conference, contributions to annual and final reports and the final-year conference, two peer-reviewed joint publications, and dissemination, exploitation and training schools.
- Milestones. M4.1 Mid-term report — Month 25; M4.2 WG4/WG5 conference — Month 34; M4.3 Database development — Month 44.
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