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Structure & People

Working Groups

Net4Brain's six working groups form one translational pipeline — WG1 to WG5 run from non-invasive biomarkers and preclinical models through tumour profiling and AI modelling to clinical recommendations, while WG6 cuts across them all to maximise dissemination and impact.

Six working groups

One translational pipeline

Explore what each working group is doing and who leads it.

WG1

WG1. Non-invasive Biomarker Discovery

Discovering sensitive and specific liquid-biopsy and radiomics biomarkers for early detection, prognosis and recurrence monitoring of brain cancer.

Leader: Prof Aida Hajdarpasic

Explore WG1

WG2

WG2. Preclinical Modelling

Development of more accurate GEMMs and PDOX models, plus 3D systems — neurospheres, organoids and bioprinting — to understand brain tumour mechanisms.

Leader: Prof Anna Golebiewska

Explore WG2

WG3

WG3. Pathogenesis and Tumour Profiling

Unravelling brain cancer pathogenesis through single-cell and multi-omics profiling for patient stratification and treatment optimisation.

Leader: Prof Tugba Bagci-Onder

Explore WG3

WG4

WG4. Mathematical & Computational Modelling

Integrating multi-omics and radiomics data with AI/ML and mathematical modelling to advance precision medicine and AI-guided practice.

Leader: Prof Claudio Angione

Explore WG4

WG5

WG5. Clinical Treatment Recommendation

Advancing radiotherapy through radiomics and multimodal -omics, refining pathological grading and personalising treatment for low- and high-risk patients.

Leader: Dr Alkinoos Athanasiou

Explore WG5

WG6

WG6. Dissemination and Exploitation

Maximising the impact of Action outputs through communication, outreach, exploitation and training, and the home of the Creative Group.

Leader: Dr Aylin Toplu

Explore WG6
How it fits together

Bench to bedside

Each working group feeds the next: biomarkers and preclinical models deepen our understanding of tumour biology, whose profiling powers the AI and mathematical models, and those models turn into clinical treatment recommendations. Dissemination and exploitation work across the whole pipeline so findings reach clinicians, patients and the public.

Get involved

Working groups welcome active contributions from Action members. Join a group and shape its next steps.